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Un’anteprima dal Corso in Neuroscienze Cognitive

Tra poco meno di un mese si terrà il Corso “Neuroscienze cognitivo/comportamentali dello sviluppo e differenze di genere: normalità e patologia”, in programma a Milano dal 13 al 15 novembre. L’affascinante tema delle differenze di genere è al centro di questa ottava edizione del Corso FM in Neuroscienze Cognitive dello Sviluppo diretto dalla d.ssa Daria Riva, primario emerito di Neuropsichiatria infantile dell’Istituto Neurologico “C. Besta”.

Presentiamo qui in anteprima l’abstract dell’intervento del prof. Harvey S. Levin del Baylor College of Medicine di Houston negli USA, focalizzato sull’influenza del sesso nel recupero del trauma cranico.Ricordiamo che il programma dettagliato del Corso, tutte le info e le modalità di iscrizione sono disponibili sul sito della Fondazione Mariani.

VAI AL PROGRAMMA: https://www.fondazione-mariani.org/it/programma-milano-2019.html
ISCRIVITI AL CORSO: https://www.fondazione-mariani.org/it/iscrizioni-milano-2019.html

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Gender differences in developmental cognitive and behavioural neuroscience: normal variation and pathology

Differences in brain morphometrics and hemispheric asymmetries have been reported between boys and girls and associated with cognitive and behavioural characteristics. Gender differences have more recently been found in brain connectivity, including anterior-posterior and left-right connections. Hormonal changes associated with the menstrual cycle have also been shown to be related to variation in brain hippocampal volume in healthy, young women. These hormones, including progesterone, have been linked to sex differences in recovery from TBI in animal models and there is preliminary evidence that steroid hormones may mediate the observed gender differences in recovery from TBI. 

Investigation of traumatic brain injury (TBI) and sports related concussion has disclosed slower recovery in females marked by more persistent and severe post-concussion symptoms and associated depression. Preclinical studies using animal models have also reported preliminary evidence for more robust axonal architecture in male than female rodents; recent, but preliminary  diffusion tensor imaging findings also show that white matter tracts of female athletes are more vulnerable to extended exposure to contact sport associated with repetitive head impacts, but other hypotheses have been advanced to explain the gender differences in recovery from TBI and sports related concussion.

Comparison of cognitive performance after TBI and sports related concussion has also shown differences between males and females which may be an accentuation of findings in typically developing adolescents and young adults. This paper will integrate developmental findings with clinical and imaging results to summarize current knowledge and directions for future research.

Harvey S. Levin

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